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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d1f0ba19ddccae820e529a02316e688ace919aba2a6f7da7f1d5a659400000' 
  AND token = 'VU2kAFJmiWTWr2TeS0ZKvLvzBD7odBW6Bpa4QhmuAPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}