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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df68bfc21d6cbc09989cf6ce8877e3f106ba482e212bb4da26f1a4cf7ffd641' 
  AND token = '3/+iOOvEJ5c/CxVlpGg5vLLKkBy2XSaEveNYNb8a6jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}