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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2647f5b6405f1127321000376d001570c2500e286ac788d6a1e0b66c90d4e6' 
  AND token = 'GbYheav0mtraEzqBlx2M7Mc3sQ/+M4eFvxJH1bYR+eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}