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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e72e7c2fff57943d859133f4c80c3f7fc19d1427113075d2d5d6022834b8f04' 
  AND token = 'vTlTJdCxdVUjxH7ZFVv1ZPxW/cIyJawAt08cmocnFjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}