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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '552c215814245466a7242e57c17dc6fa0e50fd9e40278031b66bf20dfe9148cd' 
  AND token = 'QzpP+r6COtQXSy5tOrQXmEXtqqI9+Sif6f0pVDTVpsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}