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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a02e9d27d8f06a6fc6d00a3eb4eea4f7ac459202fa944010b81eb133ef5a449' 
  AND token = 'HJjjDZhmGOo1QNce+tEsaxzSZ5fmqmL7Uy7tUDAV8EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}