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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a743b676e42300d12d18b9061b1f405d8e6489b69177c33d8dda2cce461b1ad' 
  AND token = 'O1XR0oJfy4dYw80P2fOiTSd5h5K+SlBDJbAlnN+jMV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}