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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e25fd83978a2e978bb943855ce7bbae37ac3cd50d9a3b26b6265c4bcb64e55' 
  AND token = 'B49PuS9cfvSrOSE830Tk6Lc/RPAjrNyRYeOTzQGsM+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}