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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573b2161d5a48cf79293661006507f7a22bb928489e3e0ff712d1dcf60ba1646' 
  AND token = 'HsQ4ZsMbf2WLAH0fMOSk2YU5rSNJncPBZro2ev100xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}