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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649879c7b9b5ac2dc303be6fd64da68e88b5b5047596df85f75221fd1b4f64f8' 
  AND token = 'ff4TKthXJM8T4u6NA2s7gQzRC6eeh+CbUXl3WJfC0Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}