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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72e2377d71b92665f6c499983ab4d085f55216af1c3a41458f084ab92a852e8' 
  AND token = 'WdK9M1ILx8kMV9aNGhxg94eFJBPmsvxq/ToX19CPfdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}