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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df12344ddba7419641f62296cbd913a1d3f0549983620e3bd008a0bf4adf0ea' 
  AND token = 'YbZ8Kk+EQUcL8E7zLnS1+CRMvWcGBPPgn6gDLYNdGZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}