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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ddcac78fc2d3cd23dc4a32c3d4d2b6d75342daa05b606aa94f88b81b335f9f' 
  AND token = '9p6yj526Cz7OPEUbbIxaAxYcUbCPxL83IHkw2QjRh4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}