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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18745ad7e6672b27d038abfbb605388a6c69748e3cb12a714516c7ae8dfce6fa' 
  AND token = '1Lc0N1TqNcNaKBv1VeFxrO2hqmeWO7G4j7IEMJwDiHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}