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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff67fba5281ad679f6dfdd6d3fb1042b22af03a66b0c8bd3531c29a49868d4a4' 
  AND token = 'dQ2a/8uKEIj4SU4vtxjxhZrWOc83iRRINl/eRra8tiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}