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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7bab0a75117c68c59ad7e2435b0d1a27bb26345fe8aee93779b076020e9b35' 
  AND token = 'cmODqis7u+9rEzXwUDzu5pLhUfTh9yoE2bTbxxm/ZkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}