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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150353a2887e15cff938a5cdf942daafd6837c7c0d185de5d599e57536a85e38' 
  AND token = 'DeJVXbGTYdrueczz48fRiphame7AMjNOaB2Yi/uMz6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}