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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b173efd3ebaf9cad9296da7d8f68da7497511111178ec88af3442dbfeceea1' 
  AND token = 'IldwDPSEZ7XyUE1LVqlYiR4oPm9i2om/BCnak6ubvME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}