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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235f3d6dcbeee155b6e0c3735e93d7bb4ad30c04821db807377f4d56a56d2a7f' 
  AND token = 'URhk+6MP0CuqB2mEGPP+TLVr4lVFo0TkQFoOD/KEhxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}