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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7408f998ba298c8955f3d80afcbd78e23abb24aa1f200e45e638ff051fb3f7' 
  AND token = '3fQVkNv+OvrBf99p5wT6eDF+nk39AJAKjNSaPkwKDjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}