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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae08208d217aff82556d322e2699d890a2ba33d13f1a01e3dcdb023db8861053' 
  AND token = 'XLAInCZrwc3Nb+OHF5Lo6HbhnEPupy9AD9cvJiuioh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}