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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38c51140517059fe591f8b11a29698b9fe49d748281d8f799c3803d13c18f11' 
  AND token = 'GqsHYVpY0T0tIjn46PVAV+YzWt+hvvkMIBI3PNpd2MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}