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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d275230d1ec0235e650f440021882d1e3a2646535d0517ad45254a0006b8a25' 
  AND token = 'ZG3dRXPl8KqpoGPW+iGDPPvoaS1yLXgr8nrSlI0ubdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}