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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8966fc299a41506d9242306e5bf5750a42e7f1b4e35365c7a12787b83f312ca' 
  AND token = 'E/p5ZEhkkaP1HN53k7myCFPCHb1h5ibGnVn/7ZHJlPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}