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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bd4782d8cb95d3d0100a0b483ce0f4a500c04e3acb859277de921742d70403' 
  AND token = '1KempwXfpGuXuR9QesQeo1/BaPiTMmDa2LdmtO8pEoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}