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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fb34d65e51f2c5af5a7a7edd153f4a68ee9641b3a61ee1fba93ebe9a6bd3df' 
  AND token = 'L/7OFQqs5aV3LSLdUSc78hCQpFAABuEqNQcF0e0Gh1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}