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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5336a63a1a24d81e513717406fe74518a181fca4f78909cb3f49a355ebc4ff06' 
  AND token = '9zbfE5eZRni+6bryFXcDRIxUxLDUdg75S8GWYl/1hH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}