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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d5aa27e7a0c3c32ab6917a8735696b6811020dad80b4bddb2b9df538d0236a' 
  AND token = 'XGQVUpx1h7IK3G10en/1VUYQDgee9rTe7+CMhSNoKIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}