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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34a4a37d66b00bde642ca14e19f7e8b724f6e7d708e6177bfc550f0221998500' 
  AND token = 'dudr9D9zREVidbpAVLxX1WwFyb5jR14Zcd2EDLdvGOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}