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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b061421cfd2667df7d84fb2a7dff449feecc571ad3f1d93a7154b8f48e6262af' 
  AND token = '78bUvfmenflAjCRrfmE6ffyD1SiMu9ujpMINvwN/rjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}