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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'debf41167d0359e52379aa5506333d623a51b91ebe24916de3340d834d34d2e4' 
  AND token = '647vK1FIcJt/LSOb+JVPJT8NQYQQve4lDKORlcfwzCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}