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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f59f2381fc9a12aaeee08382912eafd42b753e90fe675c7c204cd121c9e888b' 
  AND token = 'ARUE3scQ6KPWq9pdCAf0+d8t8AyjXcxWdbi42hlHB8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}