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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bebbc2ce17f876175895ec0f3845567f14f7da11bc8a6ce51bdb650be4cfb6d' 
  AND token = '1zMPDLsvLFOXE6eXBQn3uKYwrm4h1W+ixQuExADliWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}