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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500179fb3f733eb768cd865c3f95a6ffdcb09360b06e1aa4d9c394d70b365476' 
  AND token = 'O4nevR+wvDGoo4D/47DvKWxUTkbxMeL8cHKsp3qHno4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}