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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8f9023fdc7df03b05609aa67dfda33625c4140f86fa939201dc1b440f91def' 
  AND token = 'LtK1HION4FzGp89lhTq6VLCdH60JExMPVeH7v5xVjcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}