SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2e61f175c83391874185a91e79979ee3bb706b4869dd6ec91016d7f4b4eb3a' 
  AND token = 'SG0q6BD38cr0tSpF1MxpS5gcZaQvY69bNpdvTkXwwRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}