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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c750382963c41c962767079550d44fedca4ff2644f956fb2fc67f92005ed192' 
  AND token = 'Qbgb2RHoc/Z6QcNQj0C7NUAVlz7PRG1Oj7DeBj3VWh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}