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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484021f5f3411d80a60e39d655d96cef8a215e783f5cde3da26788adc5f2cf13' 
  AND token = 'DFnzV0qXFMIQCFbErhzbUrUcmVALSn+Dk4lHVWgsFPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}