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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288c352efd8e3ba8fd89a57617d6e32db8e2468985dfd9487365a7830d1983a8' 
  AND token = 'LQ0bkv5EJFqYXmJ9WEp7mDkETuwtl9xOVtYw1tXxlzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}