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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d053e77c5474569466a73dc2d8ec22bcc4a75d999c8087b65fdaca5d5bbb14c' 
  AND token = 'b2lsnW4GtB0Dg1j9iJt8JcscpNYQK/ZCd9RdJXJ/EYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}