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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2150c53da9ecaaa5608be80ab06162bad72f5f1e1d1d36d88db00f9ae5a49045' 
  AND token = 'dsPtzauLk//SliB1xLGVWL9IQH/qEsj+cAzVSgZ2D6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}