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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ed20ddede8805e2cb8ef6c6684a9baef56bce4c50c403317c500938b6dd4ac' 
  AND token = 'WI01B79dryM/iqqaed9TKItb0gziMAK7xoAoJBGHnNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}