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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144c7e85af3a382c8096c4c60e3f0708822aecb85338db3bf94cd92d8b60a4a2' 
  AND token = '0S244fWh8rBb8iDIA8hYNpHjfuzYRdWri+T9uDRQOSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}