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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b1264cbbe89a49e4669381f79e84b23333d816072c129ba0b58eceaf4e629b' 
  AND token = 'KUZmG7F2Yii4w8H6eITythzbsTAWSG2eAAPxaRhK4fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}