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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278e5a9f374d57945deea71d8603ddc3c775a36c589a8354e63f587776b876d8' 
  AND token = 'WRZ6y+MNyhZb7e29B033m7KVee8NUOPgk5gUVRvvI+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}