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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58c8c54a122830286c860043516e927492c5b6f91b34a0f72306b59b059d7b65' 
  AND token = 'jLV1PW3tB3L5Htu1S1N9rD8os+iTXdhRiF8XF0tzQTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}