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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2baa59e2ff21a55e918d8233e7fcfb9bafaab38eb349d79e6dfad1571c3fc904' 
  AND token = 'aEz788v0HVXSzrHbIm71mQ4x1aQbSCzB3Y21lqP/eFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}