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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0052dd03647d7e985330a020d6ac0dc701d12f0bde1c845320efc5a2d7470460' 
  AND token = '4+wx5E4eQbTWSN6YYnvzBA2Rsmq9Vjwc22uND+DG/pM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}