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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185d79d841331b4e08dc3aaf3cd9268f43f1ea95827b34e34969878970c1b9c7' 
  AND token = 'cihtYlTlZCNJMaVC9fx4uaNdFXmEG+zLnOyLjcv/bm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}