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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ef45a35801d91744d07c920b8f9de7d72667551d0e3117a8f0cd45e022c2c3' 
  AND token = 'ucz7r+w+pwoqHPIDw6HaRrb62tIwg7Dn3mFjNLi/nM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}